STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
pyrCDihydroorotase homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (344 aa)    
Predicted Functional Partners:
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 
 0.985
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
 
 0.979
pyrX
Dihydroorotase-like protein.
    
 0.920
carA
Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.
   
  
 0.735
carB
Carbamoyl-phosphate synthase large chain; Belongs to the CarB family.
   
  
 0.733
rsmI
Conserved hypothetical protein,predicted methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.611
purF
Glutamine amidotransferase class-II:phosphoribosyl transferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
  
 0.589
ebA312
Predicted sugar phosphatases of the HAD superfamily.
    
   0.574
ebA5780
Sugar phosphatase of the HAD superfamily.
    
   0.574
purL
Phosphoribosylformylglycinamidine synthase (FGAM synthase); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
   
  
 0.535
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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