| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| pyrC | rsmI | ebA1456 | ebA1457 | Dihydroorotase homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | Conserved hypothetical protein,predicted methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.611 |
| rpsB | rpsD | ebA5986 | ebA3852 | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 30S Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.994 |
| rpsB | rpsF | ebA5986 | ebA4075 | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 30S Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.995 |
| rpsB | rpsG | ebA5986 | ebA3822 | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.994 |
| rpsB | rpsH | ebA5986 | ebB129 | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. | 0.994 |
| rpsB | rpsN | ebA5986 | ebC1 | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. | 0.991 |
| rpsB | rpsO | ebA5986 | ebA5844 | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.994 |
| rpsB | rpsQ | ebA5986 | ebC10 | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.995 |
| rpsB | rpsR | ebA5986 | ebB142 | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 30S Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.991 |
| rpsB | rsmI | ebA5986 | ebA1457 | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | Conserved hypothetical protein,predicted methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.663 |
| rpsD | rpsB | ebA3852 | ebA5986 | 30S Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.994 |
| rpsD | rpsF | ebA3852 | ebA4075 | 30S Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 30S Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.977 |
| rpsD | rpsG | ebA3852 | ebA3822 | 30S Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.994 |
| rpsD | rpsH | ebA3852 | ebB129 | 30S Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. | 0.997 |
| rpsD | rpsN | ebA3852 | ebC1 | 30S Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. | 0.992 |
| rpsD | rpsO | ebA3852 | ebA5844 | 30S Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.991 |
| rpsD | rpsQ | ebA3852 | ebC10 | 30S Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.994 |
| rpsD | rpsR | ebA3852 | ebB142 | 30S Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 30S Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.981 |
| rpsD | rsmI | ebA3852 | ebA1457 | 30S Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | Conserved hypothetical protein,predicted methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.673 |
| rpsF | rpsB | ebA4075 | ebA5986 | 30S Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.995 |