STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
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[Homology]
Score
pdhAPutative pyruvate dehydrogenase E1 component (alpha subunit) oxidoreductase protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (362 aa)    
Predicted Functional Partners:
lpd
Pyruvate dehydrogenase multienzyme complex, Dihydrolipoamide dehydrogenase component.
 
 0.999
ebA2187
Putative pyruvate decarboxylase E1 (Beta subunit) oxidoreductase protein.
 0.999
ebA2188
Putative dihydrolipoamide acetyltransferase.
 
 0.999
aceF
Pyruvate dehydrogenase multienzyme complex, dihydrolipoamide acetyltransferase component (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.997
ldp
2-oxoglutarate dehydrogenase complex, E3 component, Dihydrolipoamide dehydrogenase.
 
 
 0.986
sucB
2-oxoglutarate dehydrogenase complex, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.973
maeB2
NADP-dependent malic enzyme.
  
 
 0.963
maeB1
NADP-dependent malic enzyme.
  
 
 0.963
pykA
Pyruvate kinase II protein; Belongs to the pyruvate kinase family.
  
 
 0.934
korA2
2-oxoglutarate ferredoxin oxidoreductase alpha subunit.
    
 0.934
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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