Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ebA2188Putative dihydrolipoamide acetyltransferase. (367 aa)    
Predicted Functional Partners:
ebA2187
Putative pyruvate decarboxylase E1 (Beta subunit) oxidoreductase protein.
 
 0.999
pdhA
Putative pyruvate dehydrogenase E1 component (alpha subunit) oxidoreductase protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.998
ldp
2-oxoglutarate dehydrogenase complex, E3 component, Dihydrolipoamide dehydrogenase.
 
 0.990
lpd
Pyruvate dehydrogenase multienzyme complex, Dihydrolipoamide dehydrogenase component.
 
 0.989
ebA2194
Predicted Acetyl-CoA synthetase.
  
 
  0.940
sucA
2-oxoglutarate dehydrogenase complex, E1 component.
  
 0.935
pta
Putative phosphate acetyltransferase (EC 2.3.1.8), gene: PTA OR RPA4567.
  
 
 0.930
pccB
Propionyl-CoA carboxylase beta subunit.
  
 
 0.928
pccA
Propionyl-CoA carboxylase, alpha subunit.
  
 0.916
ebA3640
Putative acyl CoA dehydrogenase oxidoreductase protein.
   
 0.915
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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