Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dhaLAldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa)    
Predicted Functional Partners:
adhB
Alcohol dehydrogenase II.
 
 0.952
ackA-2
Similar to acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 0.933
betB
Putative betaine aldehyde dehydrogenase (BADH) oxidoreductase protein; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.914
fdhG
Putative formaldehyde dehydrogenase (Glutathione-dependent); Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 0.914
acsA
Putative acetyl-coenzyme A synthetase.
   
 0.910
acsA-2
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.910
ebA4717
Acyl-CoA synthetase.
   
 0.910
poxB
Pyruvate oxidase; Belongs to the TPP enzyme family.
  
 0.909
ackA
Putative acetate kinase (EC 2.7.2.1),gene: ACKA OR RPA4566; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.904
ebA2194
Predicted Acetyl-CoA synthetase.
    
 0.901
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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