Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hsdSRestriction modification system specificity subunit. (424 aa)    
Predicted Functional Partners:
hsdM
Type I site-specific deoxyribonuclease,methylase subunit.
 
 
 0.998
hsdR
Type I restriction-modification system endonuclease; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.988
ebA2608
DNA-binding protein.
 
    0.970
prrC
Anticodon nuclease.
 
   
 0.955
ebA3754
Putative death-on-curing family protein.
 
    0.819
ebA675
Conserved hypothetical protein, potential type III restriction enzyme.
  
  
 0.751
ebA5924
Hypothetical protein.
  
    0.696
ebA2613
Hypothetical protein.
       0.610
atpF
F0-ATP synthase, b subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
   
 
 0.606
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.598
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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