| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cpoB | ebB84 | ebA2654 | ebB84 | Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | Predicted thioesterase. | 0.567 |
| cpoB | pal | ebA2654 | ebA2652 | Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | Outer membrane protein, porin-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.934 |
| cpoB | queC | ebA2654 | ebA2659 | Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | Similar to queC gene product; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.559 |
| cpoB | queE | ebA2654 | ebA2656 | Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | SAM radical family enzyme similar to queE gene product; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.815 |
| cpoB | tolB | ebA2654 | ebA2650 | Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | tolB protein precursor, periplasmic component of the Tol biopolymer transport system; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.979 |
| cpoB | tolR | ebA2654 | ebA2645 | Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | Biopolymer transport protein ExbD/TolR. | 0.748 |
| ebA2390 | queD | ebA2390 | ebA642 | Hypothetical protein. | Similar to queD gene product; probably involved in queuosine biosynthesis. | 0.781 |
| ebA2390 | queE | ebA2390 | ebA2656 | Hypothetical protein. | SAM radical family enzyme similar to queE gene product; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.711 |
| ebA2390 | queF | ebA2390 | ebA1782 | Hypothetical protein. | Similar to queF gene product; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.748 |
| ebB84 | cpoB | ebB84 | ebA2654 | Predicted thioesterase. | Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | 0.567 |
| ebB84 | pal | ebB84 | ebA2652 | Predicted thioesterase. | Outer membrane protein, porin-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.592 |
| ebB84 | queC | ebB84 | ebA2659 | Predicted thioesterase. | Similar to queC gene product; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.434 |
| ebB84 | queE | ebB84 | ebA2656 | Predicted thioesterase. | SAM radical family enzyme similar to queE gene product; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.577 |
| ebB84 | tolB | ebB84 | ebA2650 | Predicted thioesterase. | tolB protein precursor, periplasmic component of the Tol biopolymer transport system; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.695 |
| ebB84 | tolR | ebB84 | ebA2645 | Predicted thioesterase. | Biopolymer transport protein ExbD/TolR. | 0.847 |
| folE | queD | ebA6179 | ebA642 | Putative GTP cyclohydrolase I. | Similar to queD gene product; probably involved in queuosine biosynthesis. | 0.979 |
| folE | queE | ebA6179 | ebA2656 | Putative GTP cyclohydrolase I. | SAM radical family enzyme similar to queE gene product; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.556 |
| folE | queF | ebA6179 | ebA1782 | Putative GTP cyclohydrolase I. | Similar to queF gene product; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.490 |
| pal | cpoB | ebA2652 | ebA2654 | Outer membrane protein, porin-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | 0.934 |
| pal | ebB84 | ebA2652 | ebB84 | Outer membrane protein, porin-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | Predicted thioesterase. | 0.592 |