STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ebA2733Putative heat shock protein; Belongs to the small heat shock protein (HSP20) family. (168 aa)    
Predicted Functional Partners:
clpB
ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
 
 
 0.744
ebB88
Putative heat shock protein; Belongs to the small heat shock protein (HSP20) family.
 
    
0.731
clpA
Probable ATP-dependent protease; Belongs to the ClpA/ClpB family.
  
 
 0.709
ebA2730
Heat shock protein, HSP20 family; Belongs to the small heat shock protein (HSP20) family.
 
    
0.689
cbpA
Curved DNA-binding protein.
  
 
 0.591
ebA2737
Hypothetical protein.
   
 
 0.591
ebA2729
Hypothetical protein.
       0.573
glnA
Glutamine synthetase protein.
    
 
 0.556
hptG
Chaperone protein htpG (High temperature protein G); Molecular chaperone. Has ATPase activity.
  
 
 0.526
grpE
Putative GrpE protein (HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Severa [...]
  
 
 0.476
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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