STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
boxRPutative regulator of aerobic benzoate metabolic operon containing shikimate kinase-like domain; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (300 aa)    
Predicted Functional Partners:
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
  
 0.964
boxC
Benzoyl-CoA-dihydrodiol lyase; Enoyl-CoA-hydratase/isomerase involved in isomerisation and hydrolytic ring opening of 2,3-dihydro-2,3-diol intermediate of benzoyl-CoA.
 
   
 0.954
boxB
Benzoyl-CoA oxygenase component B.
 
     0.893
boxA
Benzoyl-CoA oxygenase component A.
 
   
 0.878
ebA2758
Conserved hypothetical protein.
 
     0.826
ebA2753
Lactonase.
 
  
 0.817
bclA
Benzoate-CoA ligase.
 
   
 0.781
bclA-2
Benzoate-CoA ligase.
  
   
 0.706
ebA2768
3-ketoadipyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.683
aroO
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily.
 
  
 0.635
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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