| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ackA-2 | ebA2840 | ebA4979 | ebA2840 | Similar to acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Transcriptional regulator, Sir2 family. | 0.522 |
| ebA2549 | ebA2840 | ebA2549 | ebA2840 | N6 adenine-specific DNA methyltransferase, N12 class. | Transcriptional regulator, Sir2 family. | 0.574 |
| ebA2549 | ebA2903 | ebA2549 | ebA2903 | N6 adenine-specific DNA methyltransferase, N12 class. | Conserved hypothetical protein. | 0.463 |
| ebA2549 | rnpA | ebA2549 | ebB90 | N6 adenine-specific DNA methyltransferase, N12 class. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.489 |
| ebA2840 | ackA-2 | ebA2840 | ebA4979 | Transcriptional regulator, Sir2 family. | Similar to acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.522 |
| ebA2840 | ebA2549 | ebA2840 | ebA2549 | Transcriptional regulator, Sir2 family. | N6 adenine-specific DNA methyltransferase, N12 class. | 0.574 |
| ebA2840 | ebA2903 | ebA2840 | ebA2903 | Transcriptional regulator, Sir2 family. | Conserved hypothetical protein. | 0.565 |
| ebA2840 | ebA775 | ebA2840 | ebA775 | Transcriptional regulator, Sir2 family. | Conserved hypothetical protein. | 0.591 |
| ebA2840 | ebB89 | ebA2840 | ebB89 | Transcriptional regulator, Sir2 family. | Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.514 |
| ebA2840 | gdhA | ebA2840 | ebA5425 | Transcriptional regulator, Sir2 family. | Glutamate/leucine/phenylalanine/valine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.644 |
| ebA2840 | rnpA | ebA2840 | ebB90 | Transcriptional regulator, Sir2 family. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.514 |
| ebA2840 | rpmH | ebA2840 | ebC7 | Transcriptional regulator, Sir2 family. | 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. | 0.518 |
| ebA2840 | thdF | ebA2840 | ebA2841 | Transcriptional regulator, Sir2 family. | Thiophene and furan oxidation protein ThdF; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.591 |
| ebA2840 | yidC | ebA2840 | ebA2842 | Transcriptional regulator, Sir2 family. | Preprotein translocase subunit yidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.570 |
| ebA2903 | ebA2549 | ebA2903 | ebA2549 | Conserved hypothetical protein. | N6 adenine-specific DNA methyltransferase, N12 class. | 0.463 |
| ebA2903 | ebA2840 | ebA2903 | ebA2840 | Conserved hypothetical protein. | Transcriptional regulator, Sir2 family. | 0.565 |
| ebA775 | ebA2840 | ebA775 | ebA2840 | Conserved hypothetical protein. | Transcriptional regulator, Sir2 family. | 0.591 |
| ebB89 | ebA2840 | ebB89 | ebA2840 | Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Transcriptional regulator, Sir2 family. | 0.514 |
| ebB89 | rnpA | ebB89 | ebB90 | Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.974 |
| ebB89 | rpmH | ebB89 | ebC7 | Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. | 0.899 |