| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ftsI | ftsQ | ebA1451 | ebB42 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division transmembrane protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.948 |
| ftsI | mrdA | ebA1451 | ebA3040 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.936 |
| ftsI | mrdB | ebA1451 | ebA3041 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Rod shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.937 |
| ftsI | mreB | ebA1451 | ebA3033 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | ROD shape-determining protein. | 0.631 |
| ftsI | mreC | ebA1451 | ebA3035 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Putative rod shape-determining MreC transmembrane protein; Involved in formation and maintenance of cell shape. | 0.773 |
| ftsI | mreD | ebA1451 | ebA3038 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Probable ROD shape-determining MRED transmembrane protein. | 0.422 |
| ftsI | murC | ebA1451 | ebA1443 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.963 |
| ftsI | murF | ebA1451 | ebA1449 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.957 |
| ftsI | murG | ebA1451 | ebA1444 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.949 |
| ftsI | rlpA | ebA1451 | ebA3043 | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Similar to rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.719 |
| ftsQ | ftsI | ebB42 | ebA1451 | Cell division transmembrane protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.948 |
| ftsQ | mrdA | ebB42 | ebA3040 | Cell division transmembrane protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.831 |
| ftsQ | mrdB | ebB42 | ebA3041 | Cell division transmembrane protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Rod shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.873 |
| ftsQ | mreD | ebB42 | ebA3038 | Cell division transmembrane protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Probable ROD shape-determining MRED transmembrane protein. | 0.752 |
| ftsQ | murC | ebB42 | ebA1443 | Cell division transmembrane protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.945 |
| ftsQ | murF | ebB42 | ebA1449 | Cell division transmembrane protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.903 |
| ftsQ | murG | ebB42 | ebA1444 | Cell division transmembrane protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.929 |
| ftsQ | rlpA | ebB42 | ebA3043 | Cell division transmembrane protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Similar to rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.723 |
| mrdA | ftsI | ebA3040 | ebA1451 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Penicillin-binding 3 precursor PBP-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.936 |
| mrdA | ftsQ | ebA3040 | ebB42 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Cell division transmembrane protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.831 |