| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSC2398 | ebA3193 | ebA4020 | ebA3193 | ATP-binding ABC transporter protein. | Putative Oxidoreductase, FAD-binding. | 0.425 |
| RSC2398 | ebA3688 | ebA4020 | ebA3688 | ATP-binding ABC transporter protein. | Probable substrate-binding periplasmic (PBP) ABC transporter protein. | 0.955 |
| RSC2398 | ebA4019 | ebA4020 | ebA4019 | ATP-binding ABC transporter protein. | Probable transmembrane ABC transporter protein, permease; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.998 |
| cobQ | ebA3688 | ebA3690 | ebA3688 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Probable substrate-binding periplasmic (PBP) ABC transporter protein. | 0.689 |
| cobQ | metH | ebA3690 | ebA3184 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.418 |
| ebA1117 | ebA3688 | ebA1117 | ebA3688 | Conserved hypothetical protein. | Probable substrate-binding periplasmic (PBP) ABC transporter protein. | 0.424 |
| ebA3193 | RSC2398 | ebA3193 | ebA4020 | Putative Oxidoreductase, FAD-binding. | ATP-binding ABC transporter protein. | 0.425 |
| ebA3193 | ebA3688 | ebA3193 | ebA3688 | Putative Oxidoreductase, FAD-binding. | Probable substrate-binding periplasmic (PBP) ABC transporter protein. | 0.564 |
| ebA3193 | ebA4019 | ebA3193 | ebA4019 | Putative Oxidoreductase, FAD-binding. | Probable transmembrane ABC transporter protein, permease; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.413 |
| ebA3193 | metH | ebA3193 | ebA3184 | Putative Oxidoreductase, FAD-binding. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.755 |
| ebA3688 | RSC2398 | ebA3688 | ebA4020 | Probable substrate-binding periplasmic (PBP) ABC transporter protein. | ATP-binding ABC transporter protein. | 0.955 |
| ebA3688 | cobQ | ebA3688 | ebA3690 | Probable substrate-binding periplasmic (PBP) ABC transporter protein. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.689 |
| ebA3688 | ebA1117 | ebA3688 | ebA1117 | Probable substrate-binding periplasmic (PBP) ABC transporter protein. | Conserved hypothetical protein. | 0.424 |
| ebA3688 | ebA3193 | ebA3688 | ebA3193 | Probable substrate-binding periplasmic (PBP) ABC transporter protein. | Putative Oxidoreductase, FAD-binding. | 0.564 |
| ebA3688 | ebA4019 | ebA3688 | ebA4019 | Probable substrate-binding periplasmic (PBP) ABC transporter protein. | Probable transmembrane ABC transporter protein, permease; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.935 |
| ebA3688 | icmF | ebA3688 | ebA3766 | Probable substrate-binding periplasmic (PBP) ABC transporter protein. | Putative adenosyl-cobalamine enzyme similar to methylmalonyl-CoA mutase or isobutyryl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.542 |
| ebA3688 | metH | ebA3688 | ebA3184 | Probable substrate-binding periplasmic (PBP) ABC transporter protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.451 |
| ebA4019 | RSC2398 | ebA4019 | ebA4020 | Probable transmembrane ABC transporter protein, permease; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | ATP-binding ABC transporter protein. | 0.998 |
| ebA4019 | ebA3193 | ebA4019 | ebA3193 | Probable transmembrane ABC transporter protein, permease; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Putative Oxidoreductase, FAD-binding. | 0.413 |
| ebA4019 | ebA3688 | ebA4019 | ebA3688 | Probable transmembrane ABC transporter protein, permease; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Probable substrate-binding periplasmic (PBP) ABC transporter protein. | 0.935 |