STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa)    
Predicted Functional Partners:
sdhA
Succinate dehydrogenase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.996
fumA
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.972
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.969
maeB2
NADP-dependent malic enzyme.
  
 
 0.967
maeB1
NADP-dependent malic enzyme.
  
 
 0.967
fdhB
Formate dehydrogenase, NAD(P) reducing, beta subunit.
   
 0.960
sdhB
Succinate dehydrogenase (Iron-sulfur subunit) oxidoreductase protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.956
sdhB-2
Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.956
sdhC
Putative succinate dehydrogenase cytochrome B subunit (Succinate dehydrogenase, cytochrome b556 subunit.
   
 
 0.950
sdhC-2
Succinate dehydrogenase cytochrome b-556 subunit (EC 1.3.99.1).
   
 
 0.950
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.