STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
pccAPropionyl-CoA carboxylase, alpha subunit. (666 aa)    
Predicted Functional Partners:
pccB
Propionyl-CoA carboxylase beta subunit.
 0.997
pta
Putative phosphate acetyltransferase (EC 2.3.1.8), gene: PTA OR RPA4567.
  
 
 0.920
ebA2188
Putative dihydrolipoamide acetyltransferase.
  
 0.916
ebA2314
Putative thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.916
ebA3640
Putative acyl CoA dehydrogenase oxidoreductase protein.
  
 0.915
acsA
Putative acetyl-coenzyme A synthetase.
  
 0.909
acsA-2
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.909
ebA4717
Acyl-CoA synthetase.
  
 0.909
prpE
Propionate-CoA ligase.
  
 0.909
accD
Putative acetyl-coenzyme A carboxylase carboxyl transferase (Subunit beta) protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 0.906
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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