STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
icmFPutative adenosyl-cobalamine enzyme similar to methylmalonyl-CoA mutase or isobutyryl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1099 aa)    
Predicted Functional Partners:
sbmB
Methylmalonyl-CoA mutase, beta subunit.
 
 
0.989
SbmB
Methylmalonyl-CoA mutase, C-terminal domain/subunit (Cobalamin-binding).
 
 
0.961
ebA2092
Conserved hypothetical protein.
 
 
0.960
argK
LAO/AO transport system kinase.
 
 
0.959
sbmA
Methylmalonyl-CoA mutase subunit alpha.
 
 
0.940
ebA3624
Predicted ABC-type Fe3+-hydroxamate transport system, periplasmic component.
 
  
 0.786
lepB
Signal peptidase I (SPase I) transmembrane protein; Belongs to the peptidase S26 family.
     
 0.683
ebA2315
Fusion of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase.
 
  
 0.677
sdhA
Succinate dehydrogenase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
     
 0.634
ebA2038
Fusion of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase.
  
  
 0.632
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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