Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
hlyDPredicted secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (334 aa)    
Predicted Functional Partners:
czcA
Probable cation efflux system protein CZCA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   
 0.932
tolC
Type I secretion outer membrane efflux protein.
 
 0.780
ebA1783
Outer membrane protein, ortholog involved in agglutination in some bacteria.
  
 0.746
macB
Transmembrane ATP-binding ABC transporter protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.668
ebB138
Conserved hypothetical protein.
       0.668
ebA1846
Similar to periplsmic HlyD type membrane fusion proteins; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.645
acrA-2
AcrA/AcrE family putative membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
0.638
ebA7103
Putative HlyD-like secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
0.624
ebA4062
HlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
  0.620
ebA6248
Similar to efflux transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.614
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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