STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
nadDPutative cytidylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (192 aa)    
Predicted Functional Partners:
rsfS
Conserved hypothetical protein,predicted iojap-related protein family; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
  
 0.968
nadE
Glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.956
ebA3399
CinA-related protein (competence-inducible); Belongs to the CinA family.
 
 
 0.942
ppnK
Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.941
ebA6868
Conserved hypothetical protein; Belongs to the CinA family.
 
 
 0.940
nadC
Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
    
 0.936
npd
NAD-dependent deacetylase 2 (sirtuin/SIR2 like protein).
   
 0.917
NPY1
NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. NudC subfamily.
     
 0.908
pntAA
Pyridine nucleotide transhydrogenase alpha subunit.
     
 0.903
pntA
Pyridine nucleotide transhydrogenase subunit alpha.
     
 0.903
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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