STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBPutative homoserine kinase protein; Belongs to the pseudomonas-type ThrB family. (313 aa)    
Predicted Functional Partners:
thrA
Homoserine dehydrogenase (EC 1.1.1.3) (HDH), gene: thrA, metL.
 
  
 0.926
thrC
Threonine synthase.
    
 0.918
thrH
Homoserine kinase.
     
 0.914
ebB140
Hypothetical protein.
  
    0.827
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.817
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.810
ebA3862
Putative aminotransferase.
   
 
  0.810
metB
Putative O-succinyl (or acetyl) homoserine (Thiol)-lyase (cystathionine gamma-synthase) protein (EC 2.5.1.48),gene: metB.
    
  0.804
metY
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49), gene: metY.
    
  0.804
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.803
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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