| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ebA3862 | metB | ebA3862 | ebA4861 | Putative aminotransferase. | Putative O-succinyl (or acetyl) homoserine (Thiol)-lyase (cystathionine gamma-synthase) protein (EC 2.5.1.48),gene: metB. | 0.918 |
| ebA3862 | metC | ebA3862 | ebA4598 | Putative aminotransferase. | Cystathionine beta-lyase, putative (EC 4.4.1.8), gene: metC. | 0.940 |
| ebA3862 | metH | ebA3862 | ebA3184 | Putative aminotransferase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.934 |
| ebA3862 | metZ | ebA3862 | ebA4785 | Putative aminotransferase. | Putative Cys/Met metabolism pyridoxal-phosphate-dependent enzyme; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.939 |
| ebA3862 | thrA | ebA3862 | ebA4952 | Putative aminotransferase. | Homoserine dehydrogenase (EC 1.1.1.3) (HDH), gene: thrA, metL. | 0.809 |
| ebA3862 | thrB | ebA3862 | ebA3979 | Putative aminotransferase. | Putative homoserine kinase protein; Belongs to the pseudomonas-type ThrB family. | 0.810 |
| ebA3862 | thrH | ebA3862 | ebA3466 | Putative aminotransferase. | Homoserine kinase. | 0.800 |
| ebB140 | thrB | ebB140 | ebA3979 | Hypothetical protein. | Putative homoserine kinase protein; Belongs to the pseudomonas-type ThrB family. | 0.843 |
| ilvE | metC | ebA993 | ebA4598 | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Cystathionine beta-lyase, putative (EC 4.4.1.8), gene: metC. | 0.919 |
| ilvE | metH | ebA993 | ebA3184 | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.460 |
| ilvE | thrA | ebA993 | ebA4952 | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Homoserine dehydrogenase (EC 1.1.1.3) (HDH), gene: thrA, metL. | 0.868 |
| ilvE | thrB | ebA993 | ebA3979 | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Putative homoserine kinase protein; Belongs to the pseudomonas-type ThrB family. | 0.810 |
| ilvE | thrH | ebA993 | ebA3466 | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Homoserine kinase. | 0.815 |
| metB | ebA3862 | ebA4861 | ebA3862 | Putative O-succinyl (or acetyl) homoserine (Thiol)-lyase (cystathionine gamma-synthase) protein (EC 2.5.1.48),gene: metB. | Putative aminotransferase. | 0.918 |
| metB | metC | ebA4861 | ebA4598 | Putative O-succinyl (or acetyl) homoserine (Thiol)-lyase (cystathionine gamma-synthase) protein (EC 2.5.1.48),gene: metB. | Cystathionine beta-lyase, putative (EC 4.4.1.8), gene: metC. | 0.871 |
| metB | metH | ebA4861 | ebA3184 | Putative O-succinyl (or acetyl) homoserine (Thiol)-lyase (cystathionine gamma-synthase) protein (EC 2.5.1.48),gene: metB. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.951 |
| metB | metZ | ebA4861 | ebA4785 | Putative O-succinyl (or acetyl) homoserine (Thiol)-lyase (cystathionine gamma-synthase) protein (EC 2.5.1.48),gene: metB. | Putative Cys/Met metabolism pyridoxal-phosphate-dependent enzyme; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.928 |
| metB | thrA | ebA4861 | ebA4952 | Putative O-succinyl (or acetyl) homoserine (Thiol)-lyase (cystathionine gamma-synthase) protein (EC 2.5.1.48),gene: metB. | Homoserine dehydrogenase (EC 1.1.1.3) (HDH), gene: thrA, metL. | 0.856 |
| metB | thrB | ebA4861 | ebA3979 | Putative O-succinyl (or acetyl) homoserine (Thiol)-lyase (cystathionine gamma-synthase) protein (EC 2.5.1.48),gene: metB. | Putative homoserine kinase protein; Belongs to the pseudomonas-type ThrB family. | 0.804 |
| metB | thrH | ebA4861 | ebA3466 | Putative O-succinyl (or acetyl) homoserine (Thiol)-lyase (cystathionine gamma-synthase) protein (EC 2.5.1.48),gene: metB. | Homoserine kinase. | 0.800 |