| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cobS | ebA3993 | ebA4005 | ebA3993 | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Conserved hypothetical protein,predicted protein kinase family. | 0.597 |
| cobS | ebA4002 | ebA4005 | ebA4002 | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Hypothetical protein. | 0.773 |
| cobS | ebA4007 | ebA4005 | ebA4007 | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | CcdB-like toxin protein. | 0.564 |
| cobS | gpmA-2 | ebA4005 | ebA4004 | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Phosphoglycerate mutase. | 0.997 |
| cobS | rfaE | ebA4005 | ebA4001 | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Similar to ADP-heptose synthase RFAE. | 0.652 |
| cobS | rfaF | ebA4005 | ebA3998 | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | ADP-heptose-LPS heptosyltransferase II. | 0.601 |
| cobS | waaC | ebA4005 | ebA3997 | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Heptosyltransferase I. | 0.604 |
| cobS | waaG | ebA4005 | ebA3996 | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | UDP-glucose:(heptosyl) LPS alpha 1,3-glucosyltransferase. | 0.665 |
| cobS | waaP | ebA4005 | ebA3995 | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Lipopolysaccharide core biosynthesis protein WaaP; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core; Belongs to the protein kinase superfamily. KdkA/rfaP family. | 0.597 |
| cobS | wcaG-2 | ebA4005 | ebA3999 | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | ADP-l-glycero-D-manno-heptose-6-epimerase (ec 5.1.3.20); Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.602 |
| ebA3993 | cobS | ebA3993 | ebA4005 | Conserved hypothetical protein,predicted protein kinase family. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.597 |
| ebA3993 | ebA4002 | ebA3993 | ebA4002 | Conserved hypothetical protein,predicted protein kinase family. | Hypothetical protein. | 0.597 |
| ebA3993 | ebA4007 | ebA3993 | ebA4007 | Conserved hypothetical protein,predicted protein kinase family. | CcdB-like toxin protein. | 0.445 |
| ebA3993 | gpmA-2 | ebA3993 | ebA4004 | Conserved hypothetical protein,predicted protein kinase family. | Phosphoglycerate mutase. | 0.607 |
| ebA3993 | rfaE | ebA3993 | ebA4001 | Conserved hypothetical protein,predicted protein kinase family. | Similar to ADP-heptose synthase RFAE. | 0.726 |
| ebA3993 | rfaF | ebA3993 | ebA3998 | Conserved hypothetical protein,predicted protein kinase family. | ADP-heptose-LPS heptosyltransferase II. | 0.832 |
| ebA3993 | waaC | ebA3993 | ebA3997 | Conserved hypothetical protein,predicted protein kinase family. | Heptosyltransferase I. | 0.897 |
| ebA3993 | waaG | ebA3993 | ebA3996 | Conserved hypothetical protein,predicted protein kinase family. | UDP-glucose:(heptosyl) LPS alpha 1,3-glucosyltransferase. | 0.947 |
| ebA3993 | waaP | ebA3993 | ebA3995 | Conserved hypothetical protein,predicted protein kinase family. | Lipopolysaccharide core biosynthesis protein WaaP; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core; Belongs to the protein kinase superfamily. KdkA/rfaP family. | 0.947 |
| ebA3993 | wcaG-2 | ebA3993 | ebA3999 | Conserved hypothetical protein,predicted protein kinase family. | ADP-l-glycero-D-manno-heptose-6-epimerase (ec 5.1.3.20); Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.773 |