STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cysGuroporphyrinogen-III methylase, c-terminal half; Belongs to the precorrin methyltransferase family. (286 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.987
hemD
Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 
 0.939
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
 0.917
cysG-2
Uroporphyrinogen-III methylase, siroheme synthase, C-terminal domain; Belongs to the precorrin methyltransferase family.
  
  
 
0.904
nirE
Uroporphyrin-III C-methyltransferase.
     
 0.902
hemB
Delta-aminolevulinic acid dehydratase (EC 4.2.1.24), gene: NE2457; Belongs to the ALAD family.
 
  
 0.869
cysI
Sulfite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.851
cobB
Cobyrinic acid a,c-diamide synthase family protein.
 
  
 0.838
ebA4029
Nitroreductase family protein.
  
  
 0.798
ebA4026
Hypothetical protein.
       0.773
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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