| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dsbC | ebA4098 | ebA4099 | ebA4098 | Putative thiol:disulphide interchange protein (Periplasmic); Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | Flavoprotein monooxygenase (probable aromatic-ring hydroxylase). | 0.753 |
| ebA4098 | dsbC | ebA4098 | ebA4099 | Flavoprotein monooxygenase (probable aromatic-ring hydroxylase). | Putative thiol:disulphide interchange protein (Periplasmic); Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | 0.753 |
| ebA4098 | ebA4291 | ebA4098 | ebA4291 | Flavoprotein monooxygenase (probable aromatic-ring hydroxylase). | Probable methyltransferase. | 0.924 |
| ebA4098 | ebA6653 | ebA4098 | ebA6653 | Flavoprotein monooxygenase (probable aromatic-ring hydroxylase). | Conserved hypothetical protein. | 0.630 |
| ebA4098 | hemF | ebA4098 | ebA1156 | Flavoprotein monooxygenase (probable aromatic-ring hydroxylase). | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.673 |
| ebA4098 | ppcB | ebA4098 | ebA3141 | Flavoprotein monooxygenase (probable aromatic-ring hydroxylase). | Beta subunit of phenylphosphate carboxylase; Belongs to the UbiD family. | 0.907 |
| ebA4098 | ppcY | ebA4098 | ebA3133 | Flavoprotein monooxygenase (probable aromatic-ring hydroxylase). | Probable UbiX-like carboxylase subunit,encoded in anaerobic phenol operon; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.910 |
| ebA4098 | ubiA | ebA4098 | ebA2294 | Flavoprotein monooxygenase (probable aromatic-ring hydroxylase). | UbiA prenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.650 |
| ebA4098 | ubiD | ebA4098 | ebA2286 | Flavoprotein monooxygenase (probable aromatic-ring hydroxylase). | Predicted 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.907 |
| ebA4098 | ubiG | ebA4098 | ebA914 | Flavoprotein monooxygenase (probable aromatic-ring hydroxylase). | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.967 |
| ebA4098 | ubiX | ebA4098 | ebA5680 | Flavoprotein monooxygenase (probable aromatic-ring hydroxylase). | 3-polyprenyl-4-hydroxybenzoate decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.910 |
| ebA4291 | ebA4098 | ebA4291 | ebA4098 | Probable methyltransferase. | Flavoprotein monooxygenase (probable aromatic-ring hydroxylase). | 0.924 |
| ebA4291 | ubiG | ebA4291 | ebA914 | Probable methyltransferase. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.922 |
| ebA6653 | ebA4098 | ebA6653 | ebA4098 | Conserved hypothetical protein. | Flavoprotein monooxygenase (probable aromatic-ring hydroxylase). | 0.630 |
| ebA6653 | ubiA | ebA6653 | ebA2294 | Conserved hypothetical protein. | UbiA prenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.425 |
| ebA6653 | ubiG | ebA6653 | ebA914 | Conserved hypothetical protein. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.647 |
| hemF | ebA4098 | ebA1156 | ebA4098 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Flavoprotein monooxygenase (probable aromatic-ring hydroxylase). | 0.673 |
| hemF | ubiA | ebA1156 | ebA2294 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | UbiA prenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.406 |
| ppcB | ebA4098 | ebA3141 | ebA4098 | Beta subunit of phenylphosphate carboxylase; Belongs to the UbiD family. | Flavoprotein monooxygenase (probable aromatic-ring hydroxylase). | 0.907 |
| ppcB | ppcY | ebA3141 | ebA3133 | Beta subunit of phenylphosphate carboxylase; Belongs to the UbiD family. | Probable UbiX-like carboxylase subunit,encoded in anaerobic phenol operon; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.990 |