Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hyfBHydrogenase-4 component B. (666 aa)    
Predicted Functional Partners:
hyfG
Subunit of formate hydrogenlyase-like membrane complex, related to large subunit of hydrogenases.
 
 
 0.997
hyfD
Formate hydrogenlyase membrane subunit subunit HyfD.
 
 
 0.991
hyfI
Subunit of putative formate hydrogenlyase-like membrane complex.
 
 
 0.987
phaA
pH adaptation potassium efflux protein.
  
 
 0.983
hyfE
Hydrogenase 4 membrane component.
 
  
 0.971
hyfF
Formate hydrogenlyase subunit, similar to NuoM subunit of complex I.
 
  
0.965
phaC
pH adaptation potassium efflux protein.
  
 
 0.942
nuoL
NADH dehydrogenase I, chain L.
 
 
0.939
phaE
Potential Na+/H+ antiporter subunit.
  
 
 0.934
phaG
Probable potassium efflux system protein.
  
 
 0.920
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
Server load: low (12%) [HD]