| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| amiC-2 | ebA4453 | ebA4451 | ebA4453 | N-acetylmuramoyl-L-alanine amidase, AMIC precursor protein. | Conserved hypothetical protein. | 0.857 |
| amiC-2 | ileS | ebA4451 | ebA4448 | N-acetylmuramoyl-L-alanine amidase, AMIC precursor protein. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.649 |
| amiC-2 | lspA | ebA4451 | ebA4447 | N-acetylmuramoyl-L-alanine amidase, AMIC precursor protein. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.626 |
| amiC-2 | nnrE | ebA4451 | ebA4962 | N-acetylmuramoyl-L-alanine amidase, AMIC precursor protein. | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.452 |
| amiC-2 | queG | ebA4451 | ebA4454 | N-acetylmuramoyl-L-alanine amidase, AMIC precursor protein. | Probable iron-sulfur 4Fe-4S ferredoxin protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.646 |
| amiC-2 | ribF | ebA4451 | ebA4449 | N-acetylmuramoyl-L-alanine amidase, AMIC precursor protein. | Probable riboflavin biosynthesis protein; Belongs to the ribF family. | 0.620 |
| ebA4453 | amiC-2 | ebA4453 | ebA4451 | Conserved hypothetical protein. | N-acetylmuramoyl-L-alanine amidase, AMIC precursor protein. | 0.857 |
| ebA4453 | ebA6494 | ebA4453 | ebA6494 | Conserved hypothetical protein. | Probable glycoprotease. | 0.963 |
| ebA4453 | gcp | ebA4453 | ebA4371 | Conserved hypothetical protein. | Probable O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.887 |
| ebA4453 | ileS | ebA4453 | ebA4448 | Conserved hypothetical protein. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.659 |
| ebA4453 | lspA | ebA4453 | ebA4447 | Conserved hypothetical protein. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.604 |
| ebA4453 | nnrE | ebA4453 | ebA4962 | Conserved hypothetical protein. | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.792 |
| ebA4453 | queG | ebA4453 | ebA4454 | Conserved hypothetical protein. | Probable iron-sulfur 4Fe-4S ferredoxin protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.622 |
| ebA4453 | ribF | ebA4453 | ebA4449 | Conserved hypothetical protein. | Probable riboflavin biosynthesis protein; Belongs to the ribF family. | 0.658 |
| ebA4453 | sua5 | ebA4453 | ebA110 | Conserved hypothetical protein. | Putative translation factor (SUA5); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.594 |
| ebA4453 | yrdC | ebA4453 | ebA6128 | Conserved hypothetical protein. | Putative translation factor YrdC/SUA5; Belongs to the SUA5 family. | 0.594 |
| ebA6494 | ebA4453 | ebA6494 | ebA4453 | Probable glycoprotease. | Conserved hypothetical protein. | 0.963 |
| ebA6494 | gcp | ebA6494 | ebA4371 | Probable glycoprotease. | Probable O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.940 |
| ebA6494 | nnrE | ebA6494 | ebA4962 | Probable glycoprotease. | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.402 |
| ebA6494 | sua5 | ebA6494 | ebA110 | Probable glycoprotease. | Putative translation factor (SUA5); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.640 |
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