Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
metCCystathionine beta-lyase, putative (EC 4.4.1.8), gene: metC. (402 aa)    
Predicted Functional Partners:
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.975
cysK
Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.973
ebA3862
Putative aminotransferase.
 
 
 0.940
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 
 0.930
tst
Thiosulfate sulfurtransferase.
 
 
 0.927
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 0.919
trxB
Thioredoxin reductase.
   
 
 0.908
trxB-2
FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
   
 
 0.908
cysE
O-acetylserine synthase.
  
 
 0.882
thrA
Homoserine dehydrogenase (EC 1.1.1.3) (HDH), gene: thrA, metL.
  
 
 0.875
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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