Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
acxBAcetone carboxylase alpha subunit. (774 aa)    
Predicted Functional Partners:
acxC
Acetone carboxylase gamma subunit.
 
 0.999
acxA
Acetone carboxylase beta subunit.
 
 
 0.984
apc3
Related to beta-subunit of acetone carboxylase, possible subunit of acetophenone carboxylase; Catalyzes the carboxylation of acetophenone to form 3-oxo-3- phenylpropanoate (benzoylacetate) in the anaerobic catabolism of ethylbenzene. Also carboxylates propiophenone at the same rate and 4- acetyl-pyridine at lower rates; Belongs to the HyuA family.
 
 
 0.942
apc2
Related to gamma-subunit of acetone carboxylase, possible subunit of acetophenone carboxylase; Catalyzes the carboxylation of acetophenone to form 3-oxo-3- phenylpropanoate (benzoylacetate) in the anaerobic catabolism of ethylbenzene. Also carboxylates propiophenone at the same rate and 4- acetyl-pyridine at lower rates.
 
 
 
 0.905
apc1
Related to beta-subunit of acetone carboxylase, possible subunit of acetophenone carboxylase; Catalyzes the carboxylation of acetophenone to form 3-oxo-3- phenylpropanoate (benzoylacetate) in the anaerobic catabolism of ethylbenzene. Also carboxylates propiophenone at the same rate and 4- acetyl-pyridine at lower rates; Belongs to the oxoprolinase family.
 
 
 0.893
hyuA
Hydantoin utilization protein A.
 
 
 0.880
acxR
Sigma-54 dependent transcriptional activator.
 
     0.636
ebA4715
Hypothetical protein.
 
     0.509
ebA4712
Probable regulatory protein, LysR.
 
     0.486
ebA4709
Predicted exporters of the RND superfamily.
 
     0.453
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
Server load: low (20%) [HD]