| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| algA | algD | ebA4723 | ebA4268 | Putative mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | GDP-mannose 6-dehydrogenase. | 0.963 |
| algA | ebA996 | ebA4723 | ebA996 | Putative mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Putative phosphoglucomutase. | 0.975 |
| algA | fbp | ebA4723 | ebA1191 | Putative mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Fructose-1,6-bisphosphatase. | 0.934 |
| algA | galE | ebA4723 | ebA3856 | Putative mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | UDP-glucose 4-epimerase, gene: SP1607; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | 0.919 |
| algA | glmS | ebA4723 | ebA2244 | Putative mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Glutamine amidotransferase class-II; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.926 |
| algA | manX | ebA4723 | ebA2794 | Putative mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Phosphotransferase, mannose/fructose-specific component IIA. | 0.919 |
| algA | pfkA | ebA4723 | ebA5088 | Putative mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.926 |
| algA | pgi | ebA4723 | ebA5208 | Putative mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Glucose-6-phosphate isomerase. | 0.951 |
| algA | ugd | ebA4723 | ebA899 | Putative mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | UDP-glucose dehydrogenase. | 0.923 |
| algA | wcaJ | ebA4723 | ebA1531 | Putative mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Colanic biosynthesis UDP-glucose lipid carrier transferase. | 0.948 |
| algD | algA | ebA4268 | ebA4723 | GDP-mannose 6-dehydrogenase. | Putative mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.963 |
| algD | manX | ebA4268 | ebA2794 | GDP-mannose 6-dehydrogenase. | Phosphotransferase, mannose/fructose-specific component IIA. | 0.800 |
| algD | wcaJ | ebA4268 | ebA1531 | GDP-mannose 6-dehydrogenase. | Colanic biosynthesis UDP-glucose lipid carrier transferase. | 0.428 |
| ebA996 | algA | ebA996 | ebA4723 | Putative phosphoglucomutase. | Putative mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.975 |
| ebA996 | manX | ebA996 | ebA2794 | Putative phosphoglucomutase. | Phosphotransferase, mannose/fructose-specific component IIA. | 0.905 |
| ebA996 | pgi | ebA996 | ebA5208 | Putative phosphoglucomutase. | Glucose-6-phosphate isomerase. | 0.929 |
| ebA996 | wcaJ | ebA996 | ebA1531 | Putative phosphoglucomutase. | Colanic biosynthesis UDP-glucose lipid carrier transferase. | 0.516 |
| fbp | algA | ebA1191 | ebA4723 | Fructose-1,6-bisphosphatase. | Putative mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.934 |
| fbp | pfkA | ebA1191 | ebA5088 | Fructose-1,6-bisphosphatase. | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.935 |
| fbp | pgi | ebA1191 | ebA5208 | Fructose-1,6-bisphosphatase. | Glucose-6-phosphate isomerase. | 0.947 |