node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cbpA | clpA | ebA2728 | ebA4477 | Curved DNA-binding protein. | Probable ATP-dependent protease; Belongs to the ClpA/ClpB family. | 0.677 |
cbpA | clpB | ebA2728 | ebA6667 | Curved DNA-binding protein. | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.677 |
cbpA | dnaK | ebA2728 | ebA4794 | Curved DNA-binding protein. | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.944 |
cbpA | groeL | ebA2728 | ebA1185 | Curved DNA-binding protein. | Chaperonin 60kD subunit; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.774 |
cbpA | groeS | ebA2728 | ebB35 | Curved DNA-binding protein. | Chaperonins cpn10 (10 kDa subunit); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.606 |
cbpA | grpE | ebA2728 | ebA4795 | Curved DNA-binding protein. | Putative GrpE protein (HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Severa [...] | 0.882 |
cbpA | hptG | ebA2728 | ebA4865 | Curved DNA-binding protein. | Chaperone protein htpG (High temperature protein G); Molecular chaperone. Has ATPase activity. | 0.908 |
clpA | cbpA | ebA4477 | ebA2728 | Probable ATP-dependent protease; Belongs to the ClpA/ClpB family. | Curved DNA-binding protein. | 0.677 |
clpA | dnaJ | ebA4477 | ebA4793 | Probable ATP-dependent protease; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.656 |
clpA | dnaJ-2 | ebA4477 | ebD108 | Probable ATP-dependent protease; Belongs to the ClpA/ClpB family. | DnaJ class protein. | 0.646 |
clpA | dnaJ1 | ebA4477 | ebA3490 | Probable ATP-dependent protease; Belongs to the ClpA/ClpB family. | Similar to chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betw [...] | 0.656 |
clpA | dnaK | ebA4477 | ebA4794 | Probable ATP-dependent protease; Belongs to the ClpA/ClpB family. | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.842 |
clpA | groeL | ebA4477 | ebA1185 | Probable ATP-dependent protease; Belongs to the ClpA/ClpB family. | Chaperonin 60kD subunit; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.648 |
clpA | groeS | ebA4477 | ebB35 | Probable ATP-dependent protease; Belongs to the ClpA/ClpB family. | Chaperonins cpn10 (10 kDa subunit); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.728 |
clpA | grpE | ebA4477 | ebA4795 | Probable ATP-dependent protease; Belongs to the ClpA/ClpB family. | Putative GrpE protein (HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Severa [...] | 0.797 |
clpA | hptG | ebA4477 | ebA4865 | Probable ATP-dependent protease; Belongs to the ClpA/ClpB family. | Chaperone protein htpG (High temperature protein G); Molecular chaperone. Has ATPase activity. | 0.753 |
clpB | cbpA | ebA6667 | ebA2728 | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Curved DNA-binding protein. | 0.677 |
clpB | dnaJ | ebA6667 | ebA4793 | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.667 |
clpB | dnaJ-2 | ebA6667 | ebD108 | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | DnaJ class protein. | 0.646 |
clpB | dnaJ1 | ebA6667 | ebA3490 | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Similar to chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betw [...] | 0.667 |