| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cbpA | clpP | ebA2728 | ebA4970 | Curved DNA-binding protein. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.420 |
| cbpA | dnaK | ebA2728 | ebA4794 | Curved DNA-binding protein. | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.944 |
| cbpA | ebA1979 | ebA2728 | ebA1979 | Curved DNA-binding protein. | DnaK-related protein. | 0.832 |
| cbpA | ebA1980 | ebA2728 | ebA1980 | Curved DNA-binding protein. | DnaK-related protein; Belongs to the heat shock protein 70 family. | 0.832 |
| cbpA | ebA3469 | ebA2728 | ebA3469 | Curved DNA-binding protein. | Molecular chaperone, Hsp70 class. | 0.844 |
| cbpA | ebA7261 | ebA2728 | ebA7261 | Curved DNA-binding protein. | Similar to Fels-1 prophage protease subunits of ATP-dependent protease; Belongs to the peptidase S14 family. | 0.420 |
| cbpA | groeL | ebA2728 | ebA1185 | Curved DNA-binding protein. | Chaperonin 60kD subunit; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.774 |
| cbpA | grpE | ebA2728 | ebA4795 | Curved DNA-binding protein. | Putative GrpE protein (HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Severa [...] | 0.882 |
| cbpA | hrcA | ebA2728 | ebA4803 | Curved DNA-binding protein. | Negative regulator of class I heat shock protein; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.719 |
| clpP | cbpA | ebA4970 | ebA2728 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Curved DNA-binding protein. | 0.420 |
| clpP | dnaK | ebA4970 | ebA4794 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.540 |
| clpP | ebA1979 | ebA4970 | ebA1979 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | DnaK-related protein. | 0.512 |
| clpP | ebA1980 | ebA4970 | ebA1980 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | DnaK-related protein; Belongs to the heat shock protein 70 family. | 0.512 |
| clpP | ebA3469 | ebA4970 | ebA3469 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Molecular chaperone, Hsp70 class. | 0.511 |
| clpP | groeL | ebA4970 | ebA1185 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperonin 60kD subunit; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.718 |
| clpP | grpE | ebA4970 | ebA4795 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Putative GrpE protein (HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Severa [...] | 0.619 |
| clpP | hrcA | ebA4970 | ebA4803 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Negative regulator of class I heat shock protein; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.750 |
| dnaK | cbpA | ebA4794 | ebA2728 | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Curved DNA-binding protein. | 0.944 |
| dnaK | clpP | ebA4794 | ebA4970 | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.540 |
| dnaK | ebA7261 | ebA4794 | ebA7261 | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Similar to Fels-1 prophage protease subunits of ATP-dependent protease; Belongs to the peptidase S14 family. | 0.540 |