Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemN-2Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (475 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.957
hemF
Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
    
 0.938
ebA1774
Conserved hypothetical membrane protein.
    
 0.917
ompW
Outer membrane protein OmpW.
 
  
 0.848
ccoN-2
Cytochrome-cbb3 oxidase, subunit I; Belongs to the heme-copper respiratory oxidase family.
 
  
 0.794
fnr
Transcription factor Fnr.
 
  
 0.779
ebA5135
Putative iron-sulfur 4Fe-4S ferredoxin transmembrane protein.
 
  
 0.768
ccoO-2
Cytochrome-cbb3 oxidase, subunit II.
 
  
 0.767
ebA5153
Conserved hypothetical protein.
 
   
 0.760
ccoN
Cytochrome C oxidase subunit transmembrane protein (EC 1.9.3.1).
 
  
 0.745
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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