STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
acnAAconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)    
Predicted Functional Partners:
gltA
Citrate synthase; Belongs to the citrate synthase family.
 
 0.994
icd
Isocitrate dehydrogenase.
 
 0.987
acnB
Aconitase; Belongs to the aconitase/IPM isomerase family.
    
0.945
icd2
Isocitrate dehydrogenase isozyme 2,monomeric type, NADP-specific; Belongs to the monomeric-type IDH family.
  
 
 0.920
aceA
Isocitrate lyase.
   
 
 0.916
acnA2
Aconitase.
  
  
 
0.903
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.882
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.825
atpA
F1-ATP synthase, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
   
 0.774
rpmF
50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
   
 0.751
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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