Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gdhAGlutamate/leucine/phenylalanine/valine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa)    
Predicted Functional Partners:
gls1
Ferredoxin-dependent glutamate synthase.
  
 0.991
lpd
Pyruvate dehydrogenase multienzyme complex, Dihydrolipoamide dehydrogenase component.
  
 
 0.955
putA
Bifunctional proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 
 0.954
argA
GCN5-related N-acetyltransferase:aspartokinase superfamily; Belongs to the acetyltransferase family. ArgA subfamily.
  
 
 0.940
glnA
Glutamine synthetase protein.
  
 
 0.934
gltA
Citrate synthase; Belongs to the citrate synthase family.
   
 0.932
gltD
Glutamate synthase, small subunit.
  
 
 0.929
argJ
Arginine biosynthesis bifunctional protein argJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
     
 0.920
gdh
NAD-glutamate dehydrogenase.
    
 0.915
icd
Isocitrate dehydrogenase.
   
 0.915
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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