| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cdsA | dxr | ebA5992 | ebA5994 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267) (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.954 |
| cdsA | ebA5985 | ebA5992 | ebA5985 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Hypothetical protein. | 0.478 |
| cdsA | ebA5995 | ebA5992 | ebA5995 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Membrane-associated Zn-dependent protease. | 0.926 |
| cdsA | frr | ebA5992 | ebA5990 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.808 |
| cdsA | glnD | ebA5992 | ebA5982 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and met [...] | 0.430 |
| cdsA | map | ebA5992 | ebA5984 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.430 |
| cdsA | pyrH | ebA5992 | ebA5988 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.904 |
| cdsA | rpsB | ebA5992 | ebA5986 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.559 |
| cdsA | tsf | ebA5992 | ebA5987 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.772 |
| cdsA | uppS | ebA5992 | ebA5991 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.977 |
| dxr | cdsA | ebA5994 | ebA5992 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267) (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.954 |
| dxr | ebA5985 | ebA5994 | ebA5985 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267) (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Hypothetical protein. | 0.478 |
| dxr | ebA5995 | ebA5994 | ebA5995 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267) (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Membrane-associated Zn-dependent protease. | 0.910 |
| dxr | frr | ebA5994 | ebA5990 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267) (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.801 |
| dxr | glnD | ebA5994 | ebA5982 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267) (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and met [...] | 0.497 |
| dxr | map | ebA5994 | ebA5984 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267) (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.513 |
| dxr | pyrH | ebA5994 | ebA5988 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267) (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.791 |
| dxr | rpsB | ebA5994 | ebA5986 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267) (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.613 |
| dxr | tsf | ebA5994 | ebA5987 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267) (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.829 |
| dxr | uppS | ebA5994 | ebA5991 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267) (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.971 |