| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaL | lig | ebA7094 | ebA6380 | DNA ligase, ATP-dependent. | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.915 |
| dnaL | polA | ebA7094 | ebA3982 | DNA ligase, ATP-dependent. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.888 |
| ebA6382 | epsT | ebA6382 | ebA6378 | Probable zipA related protein, possibly involved in cell division; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family. | UDP-glucose pyrophosphorylase EpsT. | 0.717 |
| ebA6382 | lig | ebA6382 | ebA6380 | Probable zipA related protein, possibly involved in cell division; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family. | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.827 |
| ebA6382 | smc | ebA6382 | ebA6384 | Probable zipA related protein, possibly involved in cell division; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family. | Chromosome segregation ATPase; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.628 |
| ebA650 | lig | ebA650 | ebA6380 | Sun homolog protein. | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.617 |
| epsT | ebA6382 | ebA6378 | ebA6382 | UDP-glucose pyrophosphorylase EpsT. | Probable zipA related protein, possibly involved in cell division; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family. | 0.717 |
| epsT | lig | ebA6378 | ebA6380 | UDP-glucose pyrophosphorylase EpsT. | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.723 |
| epsT | smc | ebA6378 | ebA6384 | UDP-glucose pyrophosphorylase EpsT. | Chromosome segregation ATPase; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.546 |
| leuS | lig | ebA4386 | ebA6380 | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.848 |
| leuS | polA | ebA4386 | ebA3982 | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.647 |
| lig | dnaL | ebA6380 | ebA7094 | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | DNA ligase, ATP-dependent. | 0.915 |
| lig | ebA6382 | ebA6380 | ebA6382 | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Probable zipA related protein, possibly involved in cell division; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family. | 0.827 |
| lig | ebA650 | ebA6380 | ebA650 | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Sun homolog protein. | 0.617 |
| lig | epsT | ebA6380 | ebA6378 | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | UDP-glucose pyrophosphorylase EpsT. | 0.723 |
| lig | leuS | ebA6380 | ebA4386 | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.848 |
| lig | nusB | ebA6380 | ebA3564 | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | N utilization substance protein B,transcription termination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.603 |
| lig | polA | ebA6380 | ebA3982 | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.726 |
| lig | smc | ebA6380 | ebA6384 | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Chromosome segregation ATPase; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.643 |
| lig | sun | ebA6380 | ebA2833 | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | tRNA and rRNA cytosine-C5-methylases sun; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.617 |