node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apbA | panB | ebA232 | ebA7119 | Ketopantoate reductase ApbA; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.989 |
apbA | panC | ebA232 | ebA7120 | Ketopantoate reductase ApbA; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.936 |
folK | panB | ebA7113 | ebA7119 | 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokin ase. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.738 |
folK | panC | ebA7113 | ebA7120 | 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokin ase. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.739 |
folK | pcnB | ebA7113 | ebA7112 | 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokin ase. | RNA-poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.950 |
guaA | ilvD | ebA6645 | ebA1822 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.471 |
guaA | ilvD-2 | ebA6645 | ebA6761 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Dihydroxy-acid dehydratase 3; Belongs to the IlvD/Edd family. | 0.548 |
guaA | ilvD1 | ebA6645 | ebA478 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Dihydroxy-acid dehydratase 3; Belongs to the IlvD/Edd family. | 0.549 |
guaA | panB | ebA6645 | ebA7119 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.581 |
guaA | panC | ebA6645 | ebA7120 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.512 |
ilvD | guaA | ebA1822 | ebA6645 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.471 |
ilvD | ilvD-2 | ebA1822 | ebA6761 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Dihydroxy-acid dehydratase 3; Belongs to the IlvD/Edd family. | 0.906 |
ilvD | ilvD1 | ebA1822 | ebA478 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Dihydroxy-acid dehydratase 3; Belongs to the IlvD/Edd family. | 0.906 |
ilvD | ilvE | ebA1822 | ebA993 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.966 |
ilvD | panB | ebA1822 | ebA7119 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.911 |
ilvD-2 | guaA | ebA6761 | ebA6645 | Dihydroxy-acid dehydratase 3; Belongs to the IlvD/Edd family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.548 |
ilvD-2 | ilvD | ebA6761 | ebA1822 | Dihydroxy-acid dehydratase 3; Belongs to the IlvD/Edd family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.906 |
ilvD-2 | ilvD1 | ebA6761 | ebA478 | Dihydroxy-acid dehydratase 3; Belongs to the IlvD/Edd family. | Dihydroxy-acid dehydratase 3; Belongs to the IlvD/Edd family. | 0.900 |
ilvD-2 | ilvE | ebA6761 | ebA993 | Dihydroxy-acid dehydratase 3; Belongs to the IlvD/Edd family. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.966 |
ilvD-2 | panB | ebA6761 | ebA7119 | Dihydroxy-acid dehydratase 3; Belongs to the IlvD/Edd family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.911 |