Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pepNProbable aminopeptidase N (Alpha-aminoacylpeptide hydrolase). (900 aa)    
Predicted Functional Partners:
pepA
Putative cytosolic aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
 0.923
ebA2547
Putative glutamate-cysteine ligase.
   
 
 0.913
gshB
Glutathione synthetase (GSH synthetase); Belongs to the prokaryotic GSH synthase family.
    
 0.910
ggt
Gamma-glutamyltranspeptidase precursor.
     
 0.902
ebA6981
Hypothetical protein, predicted Glutamate--cysteine ligase.
     
  0.900
glyA
Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.844
cysK
Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
 0.825
metC
Cystathionine beta-lyase, putative (EC 4.4.1.8), gene: metC.
  
 
 0.814
ebA3862
Putative aminotransferase.
     
  0.800
hyfG
Subunit of formate hydrogenlyase-like membrane complex, related to large subunit of hydrogenases.
   
   0.571
Your Current Organism:
Aromatoleum aromaticum
NCBI taxonomy Id: 76114
Other names: A. aromaticum EbN1, Aromatoleum aromaticum EbN1, Aromatoleum aromaticum str. EbN1, Aromatoleum aromaticum strain EbN1, Azoarcus sp. EbN1
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