Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEI48538.1Two component transcriptional regulator, winged helix family. (229 aa)    
Predicted Functional Partners:
AEI48537.1
Integral membrane sensor signal transduction histidine kinase.
 
   0.933
AEI51397.1
Multi-sensor hybrid histidine kinase.
  
 
 0.923
AEI48656.1
Multi-sensor hybrid histidine kinase.
 
 
 0.905
AEI48626.1
Integral membrane sensor signal transduction histidine kinase.
 
   0.830
AEI50178.1
Integral membrane sensor signal transduction histidine kinase.
 
   0.804
AEI47955.1
Integral membrane sensor signal transduction histidine kinase.
 
 
 0.799
AEI51818.1
PAS/PAC sensor signal transduction histidine kinase.
  
   0.786
AEI51622.1
PAS/PAC sensor signal transduction histidine kinase.
 
 
 0.785
AEI51552.1
PAS/PAC sensor signal transduction histidine kinase.
 
 
 0.782
AEI48846.1
Integral membrane sensor signal transduction histidine kinase.
  
   0.772
Your Current Organism:
Runella slithyformis
NCBI taxonomy Id: 761193
Other names: R. slithyformis DSM 19594, Runella slithyformis DSM 19594, Runella slithyformis str. DSM 19594, Runella slithyformis strain DSM 19594
Server load: low (14%) [HD]