STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RR48_08307SH3 and PX domain-containing protein 2B. (298 aa)    
Predicted Functional Partners:
RR48_03080
Histone H2A deubiquitinase MYSM1.
    
 0.883
RR48_02592
Uncharacterized protein.
  
 0.735
RR48_03188
Actin-like protein 6A; Belongs to the actin family.
    
 0.725
RR48_04115
Putative dynactin subunit 2.
    
 0.708
RR48_08466
Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
   
 0.708
RR48_03514
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
    
 0.700
RR48_02120
G1/S-specific cyclin-E; Belongs to the cyclin family.
   
 
 0.699
RR48_03444
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.692
RR48_14210
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
   
 0.690
RR48_05889
Actin-related protein 2/3 complex subunit 3.
   
 0.688
Your Current Organism:
Papilio machaon
NCBI taxonomy Id: 76193
Other names: Old World swallowtail, P. machaon, artemisia swallowtail, common yellow swallowtail
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.