STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RR48_09326Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (511 aa)    
Predicted Functional Partners:
RR48_00231
GMP synthase [glutamine-hydrolyzing].
 
 0.987
RR48_01405
GMP synthase [glutamine-hydrolyzing].
 
 0.987
RR48_00660
Adenylosuccinate synthetase isozyme 1.
  
 
 0.984
RR48_13891
AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
  
 0.955
RR48_03050
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
  
 0.933
RR48_12476
Bifunctional purine biosynthesis protein PURH.
  
 
 0.929
RR48_07199
rRNA 2'-O-methyltransferase fibrillarin.
   
    0.926
RR48_11292
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
  
  
0.925
RR48_07435
Cytosolic purine 5'-nucleotidase.
   
 
 0.925
RR48_05171
Ectonucleoside triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family.
   
 
 0.910
Your Current Organism:
Papilio machaon
NCBI taxonomy Id: 76193
Other names: Old World swallowtail, P. machaon, artemisia swallowtail, common yellow swallowtail
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