Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
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Co-expression
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[Homology]
Score
pyrXDihydroorotase. (429 aa)    
Predicted Functional Partners:
pyrB1
Aspartate carbamoyltransferase 1.
 
 0.999
pyrB2
Aspartate carbamoyltransferase 2; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
  
 0.986
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.978
ADP13766.1
Amidohydrolase family protein 4.
  
  
 
0.928
pyrC
Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
    
 0.910
ADP13966.1
Acyltransferase family protein 1.
  
    0.869
ADP13963.1
Holliday junction resolvase-like protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
  
    0.843
carA
Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.
 
  
 0.826
carB
Carbamoyl-phosphate synthase large chain; Belongs to the CarB family.
 
 
 0.822
ADP13962.1
Hypothetical protein; Belongs to the UPF0301 (AlgH) family.
       0.804
Your Current Organism:
Achromobacter xylosoxidans
NCBI taxonomy Id: 762376
Other names: A. xylosoxidans A8, Achromobacter xylosoxidans A8, Achromobacter xylosoxidans str. A8, Achromobacter xylosoxidans strain A8
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