| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADP14052.1 | ADP14899.1 | AXYL_00695 | AXYL_01561 | Pyridoxal-phosphate dependent enzyme family protein 2. | Pyridoxal-phosphate dependent enzyme family protein 4. | 0.935 |
| ADP14052.1 | glyA1 | AXYL_00695 | AXYL_00671 | Pyridoxal-phosphate dependent enzyme family protein 2. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.912 |
| ADP14052.1 | leuB1 | AXYL_00695 | AXYL_02236 | Pyridoxal-phosphate dependent enzyme family protein 2. | 3-isopropylmalate dehydrogenase 1; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.938 |
| ADP14052.1 | leuB2 | AXYL_00695 | AXYL_03894 | Pyridoxal-phosphate dependent enzyme family protein 2. | 3-isopropylmalate dehydrogenase 2. | 0.928 |
| ADP14052.1 | sdaA | AXYL_00695 | AXYL_01809 | Pyridoxal-phosphate dependent enzyme family protein 2. | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.923 |
| ADP14052.1 | thrC | AXYL_00695 | AXYL_01902 | Pyridoxal-phosphate dependent enzyme family protein 2. | Threonine synthase. | 0.952 |
| ADP14052.1 | trpA1 | AXYL_00695 | AXYL_01527 | Pyridoxal-phosphate dependent enzyme family protein 2. | Tryptophan synthase, alpha subunit 1; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.913 |
| ADP14052.1 | trpA2 | AXYL_00695 | AXYL_05438 | Pyridoxal-phosphate dependent enzyme family protein 2. | Tryptophan synthase, alpha subunit 2; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.913 |
| ADP14052.1 | trpB1 | AXYL_00695 | AXYL_01526 | Pyridoxal-phosphate dependent enzyme family protein 2. | Tryptophan synthase, beta subunit 1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.931 |
| ADP14052.1 | trpB2 | AXYL_00695 | AXYL_05439 | Pyridoxal-phosphate dependent enzyme family protein 2. | Tryptophan synthase, beta subunit 2; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.931 |
| ADP14899.1 | ADP14052.1 | AXYL_01561 | AXYL_00695 | Pyridoxal-phosphate dependent enzyme family protein 4. | Pyridoxal-phosphate dependent enzyme family protein 2. | 0.935 |
| ADP14899.1 | leuB2 | AXYL_01561 | AXYL_03894 | Pyridoxal-phosphate dependent enzyme family protein 4. | 3-isopropylmalate dehydrogenase 2. | 0.441 |
| ADP14899.1 | thrC | AXYL_01561 | AXYL_01902 | Pyridoxal-phosphate dependent enzyme family protein 4. | Threonine synthase. | 0.900 |
| glyA1 | ADP14052.1 | AXYL_00671 | AXYL_00695 | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Pyridoxal-phosphate dependent enzyme family protein 2. | 0.912 |
| glyA1 | sdaA | AXYL_00671 | AXYL_01809 | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.970 |
| glyA1 | trpA1 | AXYL_00671 | AXYL_01527 | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase, alpha subunit 1; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.913 |
| glyA1 | trpA2 | AXYL_00671 | AXYL_05438 | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase, alpha subunit 2; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.912 |
| glyA1 | trpB1 | AXYL_00671 | AXYL_01526 | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase, beta subunit 1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.912 |
| glyA1 | trpB2 | AXYL_00671 | AXYL_05439 | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase, beta subunit 2; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.912 |
| leuB1 | ADP14052.1 | AXYL_02236 | AXYL_00695 | 3-isopropylmalate dehydrogenase 1; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Pyridoxal-phosphate dependent enzyme family protein 2. | 0.938 |