def1 protein (Achromobacter xylosoxidans) - STRING interaction network

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def1

Peptide deformylase 1; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (177 aa)

Predicted Functional Partners:

rplT

0.812

rplU

0.805

rplI

0.769

rplV

0.768

tig

0.766

rplD

0.747

rpsC

0.746

phnW

0.745

rpsQ

0.741

rpsP

0.737

Your Current Organism:

Achromobacter xylosoxidans

NCBI taxonomy Id: 762376
Other names: A. xylosoxidans A8, Achromobacter xylosoxidans A8, Achromobacter xylosoxidans str. A8, Achromobacter xylosoxidans strain A8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
def1	phnW	AXYL_00875	AXYL_00877	Peptide deformylase 1; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	2-aminoethylphosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.	0.745
def1	rplD	AXYL_00875	AXYL_06456	Peptide deformylase 1; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.747
def1	rplI	AXYL_00875	AXYL_01840	Peptide deformylase 1; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L9; Binds to the 23S rRNA.	0.769
def1	rplT	AXYL_00875	AXYL_02274	Peptide deformylase 1; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.812
def1	rplU	AXYL_00875	AXYL_06052	Peptide deformylase 1; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.805
def1	rplV	AXYL_00875	AXYL_06452	Peptide deformylase 1; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.768
def1	rpsC	AXYL_00875	AXYL_06451	Peptide deformylase 1; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.	0.746
def1	rpsP	AXYL_00875	AXYL_02166	Peptide deformylase 1; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.737
def1	rpsQ	AXYL_00875	AXYL_06448	Peptide deformylase 1; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.	0.741
def1	tig	AXYL_00875	AXYL_03972	Peptide deformylase 1; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.766
phnW	def1	AXYL_00877	AXYL_00875	2-aminoethylphosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.	Peptide deformylase 1; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.745
rplD	def1	AXYL_06456	AXYL_00875	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	Peptide deformylase 1; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.747
rplD	rplI	AXYL_06456	AXYL_01840	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	Ribosomal protein L9; Binds to the 23S rRNA.	0.993
rplD	rplT	AXYL_06456	AXYL_02274	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.993
rplD	rplU	AXYL_06456	AXYL_06052	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.992
rplD	rplV	AXYL_06456	AXYL_06452	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.999
rplD	rpsC	AXYL_06456	AXYL_06451	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.	0.999
rplD	rpsP	AXYL_06456	AXYL_02166	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.990
rplD	rpsQ	AXYL_06456	AXYL_06448	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.	0.999
rplD	tig	AXYL_06456	AXYL_03972	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.985

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