STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADP14247.1itaconyl-CoA hydratase. (276 aa)    
Predicted Functional Partners:
ADP14249.1
HpcH/HpaI aldolase/citrate lyase family protein 1; Belongs to the HpcH/HpaI aldolase family.
 
 
 0.989
ADP14248.1
CoA-transferase family III family protein 5; Belongs to the CoA-transferase III family.
 
 
  0.988
ADP14636.1
CoA-transferase family III family protein 10; Belongs to the CoA-transferase III family.
 
 
  0.943
ADP15957.1
CoA-transferase family III family protein 17; Belongs to the CoA-transferase III family.
 
 
  0.942
sucD
succinyl-CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
  0.907
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
  0.906
ADP14776.1
Glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein 6.
  
  
 0.769
ADP16672.1
acyl-CoA dehydrogenase, N-terminal domain protein 10.
 
  
 0.731
ADP14250.1
PfkB family carbohydrate kinase family protein 2; Belongs to the carbohydrate kinase PfkB family.
       0.674
ADP16673.1
MmgE/PrpD family protein 3.
 
  
 0.670
Your Current Organism:
Achromobacter xylosoxidans
NCBI taxonomy Id: 762376
Other names: A. xylosoxidans A8, Achromobacter xylosoxidans A8, Achromobacter xylosoxidans str. A8, Achromobacter xylosoxidans strain A8
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