Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
merAMercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (562 aa)    
Predicted Functional Partners:
merT
Mercuric transport protein.
 
  
 0.974
merP
Mercuric transport protein periplasmic component; Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
 
  
 0.964
ADP14744.1
Transketolase, C-terminal domain protein 1.
  
 0.956
ADP19228.1
Dehydrogenase E1 component.
  
 0.956
merR
Hg(II)-responsive transcriptional regulator.
 
  
 0.940
sodC
Superoxide dismutase (Cu-Zn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
  
 0.842
ADP14471.1
Copper-translocating P-type ATPase 2.
 
 
 0.813
ADP14746.1
Alpha/beta hydrolase fold family protein 6.
 
 0.767
bkdB
Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex.
 
 0.743
lpdA3
Dihydrolipoyl dehydrogenase 3.
 
0.738
Your Current Organism:
Achromobacter xylosoxidans
NCBI taxonomy Id: 762376
Other names: A. xylosoxidans A8, Achromobacter xylosoxidans A8, Achromobacter xylosoxidans str. A8, Achromobacter xylosoxidans strain A8
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