ADP14499.1 protein (Achromobacter xylosoxidans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ADP14499.1

Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 2; Belongs to the TPP enzyme family. (543 aa)

Predicted Functional Partners:

ilvC

0.901

ilvN

0.810

ilvD2

0.743

ilvD3

0.741

katA1

0.727

atrC

0.676

leuB2

0.676

ADP16407.1

0.672

ilvD1

0.670

ADP16412.1

0.670

Your Current Organism:

Achromobacter xylosoxidans

NCBI taxonomy Id: 762376
Other names: A. xylosoxidans A8, Achromobacter xylosoxidans A8, Achromobacter xylosoxidans str. A8, Achromobacter xylosoxidans strain A8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADP14499.1	ADP16407.1	AXYL_01156	AXYL_03087	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 2; Belongs to the TPP enzyme family.	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 4; Belongs to the TPP enzyme family.	0.672
ADP14499.1	ADP16412.1	AXYL_01156	AXYL_03092	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 2; Belongs to the TPP enzyme family.	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 5; Belongs to the TPP enzyme family.	0.670
ADP14499.1	atrC	AXYL_01156	AXYL_00539	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 2; Belongs to the TPP enzyme family.	Acetolactate synthase catalytic subunit; Belongs to the TPP enzyme family.	0.676
ADP14499.1	ilvC	AXYL_01156	AXYL_01240	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 2; Belongs to the TPP enzyme family.	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	0.901
ADP14499.1	ilvD1	AXYL_01156	AXYL_00765	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 2; Belongs to the TPP enzyme family.	Dihydroxy-acid dehydratase 1; Belongs to the IlvD/Edd family.	0.670
ADP14499.1	ilvD2	AXYL_01156	AXYL_03789	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 2; Belongs to the TPP enzyme family.	Dihydroxy-acid dehydratase 2; Belongs to the IlvD/Edd family.	0.743
ADP14499.1	ilvD3	AXYL_01156	AXYL_05937	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 2; Belongs to the TPP enzyme family.	Dihydroxy-acid dehydratase 3; Belongs to the IlvD/Edd family.	0.741
ADP14499.1	ilvN	AXYL_01156	AXYL_01239	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 2; Belongs to the TPP enzyme family.	Acetolactate synthase, small subunit.	0.810
ADP14499.1	katA1	AXYL_01156	AXYL_01157	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 2; Belongs to the TPP enzyme family.	Catalase 1; Belongs to the catalase family.	0.727
ADP14499.1	leuB2	AXYL_01156	AXYL_03894	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 2; Belongs to the TPP enzyme family.	3-isopropylmalate dehydrogenase 2.	0.676
ADP16407.1	ADP14499.1	AXYL_03087	AXYL_01156	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 4; Belongs to the TPP enzyme family.	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 2; Belongs to the TPP enzyme family.	0.672
ADP16407.1	ADP16412.1	AXYL_03087	AXYL_03092	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 4; Belongs to the TPP enzyme family.	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 5; Belongs to the TPP enzyme family.	0.607
ADP16407.1	atrC	AXYL_03087	AXYL_00539	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 4; Belongs to the TPP enzyme family.	Acetolactate synthase catalytic subunit; Belongs to the TPP enzyme family.	0.670
ADP16407.1	ilvC	AXYL_03087	AXYL_01240	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 4; Belongs to the TPP enzyme family.	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	0.980
ADP16407.1	ilvD1	AXYL_03087	AXYL_00765	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 4; Belongs to the TPP enzyme family.	Dihydroxy-acid dehydratase 1; Belongs to the IlvD/Edd family.	0.801
ADP16407.1	ilvD2	AXYL_03087	AXYL_03789	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 4; Belongs to the TPP enzyme family.	Dihydroxy-acid dehydratase 2; Belongs to the IlvD/Edd family.	0.822
ADP16407.1	ilvD3	AXYL_03087	AXYL_05937	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 4; Belongs to the TPP enzyme family.	Dihydroxy-acid dehydratase 3; Belongs to the IlvD/Edd family.	0.653
ADP16407.1	ilvN	AXYL_03087	AXYL_01239	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 4; Belongs to the TPP enzyme family.	Acetolactate synthase, small subunit.	0.848
ADP16407.1	katA1	AXYL_03087	AXYL_01157	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 4; Belongs to the TPP enzyme family.	Catalase 1; Belongs to the catalase family.	0.462
ADP16407.1	leuB2	AXYL_03087	AXYL_03894	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 4; Belongs to the TPP enzyme family.	3-isopropylmalate dehydrogenase 2.	0.830

page 1 of 5

Server load: low (22%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About