STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
prpEpropionate--CoA ligase. (629 aa)    
Predicted Functional Partners:
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
 
  
 
0.947
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
  
 0.932
ADP14954.1
AMP-binding enzyme family protein 5.
  
  
 
0.925
ADP15730.1
AMP-binding enzyme family protein 9.
  
  
 
0.921
mmsA1
Methylmalonate-semialdehyde dehydrogenase (acylating) 1.
  
 0.916
mmsA2
Methylmalonate-semialdehyde dehydrogenase (acylating) 2.
  
 0.916
mmsA3
Methylmalonate-semialdehyde dehydrogenase (acylating) 3.
  
 0.916
bkdB
Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex.
  
 
 0.910
qor2
Quinone oxidoreductase 2.
  
 
 0.910
ADP19134.1
Quinone oxidoreductase, YhdH/YhfP family protein 1.
  
 
 0.910
Your Current Organism:
Achromobacter xylosoxidans
NCBI taxonomy Id: 762376
Other names: A. xylosoxidans A8, Achromobacter xylosoxidans A8, Achromobacter xylosoxidans str. A8, Achromobacter xylosoxidans strain A8
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