Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
prpD2-methylcitrate dehydratase. (483 aa)    
Predicted Functional Partners:
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
 
 0.995
prpF
AcnD-accessory protein PrpF.
  
 
 0.962
prpB1
Methylisocitrate lyase 1; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
  
 0.944
acnA2
Aconitate hydratase 2; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.921
acnA3
Aconitate hydratase 3.
  
 
 0.921
acnD
2-methylisocitrate dehydratase, Fe/S-dependent.
  
 
 0.921
acnA4
Aconitate hydratase 4; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.921
acnA1
Aconitate hydratase 1; Belongs to the aconitase/IPM isomerase family.
     
 0.917
ADP19307.1
Isocitrate lyase family protein.
 
  
 0.817
prpB2
Methylisocitrate lyase 2.
 
  
 0.801
Your Current Organism:
Achromobacter xylosoxidans
NCBI taxonomy Id: 762376
Other names: A. xylosoxidans A8, Achromobacter xylosoxidans A8, Achromobacter xylosoxidans str. A8, Achromobacter xylosoxidans strain A8
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