| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADP15612.1 | ADP15613.1 | AXYL_02291 | AXYL_02292 | Bacterial regulatory helix-turn-helix protein, LysR family protein 58; Belongs to the LysR transcriptional regulatory family. | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein 4. | 0.532 |
| ADP15613.1 | ADP15612.1 | AXYL_02292 | AXYL_02291 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein 4. | Bacterial regulatory helix-turn-helix protein, LysR family protein 58; Belongs to the LysR transcriptional regulatory family. | 0.532 |
| ADP15613.1 | ADP18853.1 | AXYL_02292 | AXYL_05553 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein 4. | Zinc-binding dehydrogenase family protein 10. | 0.484 |
| ADP15613.1 | gcvH | AXYL_02292 | AXYL_05635 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein 4. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.408 |
| ADP15613.1 | metH | AXYL_02292 | AXYL_00509 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein 4. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.460 |
| ADP15613.1 | pyk | AXYL_02292 | AXYL_00872 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein 4. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.440 |
| ADP15613.1 | sucD | AXYL_02292 | AXYL_01877 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein 4. | succinyl-CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.401 |
| ADP15613.1 | tal | AXYL_02292 | AXYL_04994 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein 4. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.435 |
| ADP18853.1 | ADP15613.1 | AXYL_05553 | AXYL_02292 | Zinc-binding dehydrogenase family protein 10. | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein 4. | 0.484 |
| ADP18853.1 | gcvH | AXYL_05553 | AXYL_05635 | Zinc-binding dehydrogenase family protein 10. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.420 |
| gcvH | ADP15613.1 | AXYL_05635 | AXYL_02292 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein 4. | 0.408 |
| gcvH | ADP18853.1 | AXYL_05635 | AXYL_05553 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Zinc-binding dehydrogenase family protein 10. | 0.420 |
| gcvH | metH | AXYL_05635 | AXYL_00509 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.524 |
| metH | ADP15613.1 | AXYL_00509 | AXYL_02292 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein 4. | 0.460 |
| metH | gcvH | AXYL_00509 | AXYL_05635 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.524 |
| metH | pyk | AXYL_00509 | AXYL_00872 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.414 |
| pyk | ADP15613.1 | AXYL_00872 | AXYL_02292 | Pyruvate kinase; Belongs to the pyruvate kinase family. | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein 4. | 0.440 |
| pyk | metH | AXYL_00872 | AXYL_00509 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.414 |
| pyk | sucD | AXYL_00872 | AXYL_01877 | Pyruvate kinase; Belongs to the pyruvate kinase family. | succinyl-CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.548 |
| pyk | tal | AXYL_00872 | AXYL_04994 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.928 |
