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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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ADP15807.1Dehydratase family protein 3; Belongs to the IlvD/Edd family. (591 aa)    
Predicted Functional Partners:
ilvB1
Acetolactate synthase, large subunit, biosynthetic type 1.
 
 
 0.805
ilvB3
Acetolactate synthase, large subunit, biosynthetic type 3.
 
 
 0.795
ADP15806.1
Bacterial regulatory protein, GntR family protein 23.
       0.781
atrC
Acetolactate synthase catalytic subunit; Belongs to the TPP enzyme family.
 
 
 0.771
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.753
ilvN
Acetolactate synthase, small subunit.
 
 
 0.704
ADP16407.1
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 4; Belongs to the TPP enzyme family.
 
 
 0.701
ADP18002.1
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 7; Belongs to the TPP enzyme family.
 
 
 0.686
ilvB2
Acetolactate synthase, large subunit, biosynthetic type 2; Belongs to the TPP enzyme family.
 
 
 0.662
ADP16412.1
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 5; Belongs to the TPP enzyme family.
 
 
 0.654
Your Current Organism:
Achromobacter xylosoxidans
NCBI taxonomy Id: 762376
Other names: A. xylosoxidans A8, Achromobacter xylosoxidans A8, Achromobacter xylosoxidans str. A8, Achromobacter xylosoxidans strain A8
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