STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADP15880.1Penicillin G acylase. (860 aa)    
Predicted Functional Partners:
ADP16457.1
Penicillin amidase family protein 2.
  
  
 
0.928
ADP15879.1
Bacterial regulatory helix-turn-helix protein, LysR family protein 72; Belongs to the LysR transcriptional regulatory family.
       0.536
ADP13637.1
Hypothetical protein.
  
     0.524
ADP18800.1
Esterase family protein 2.
  
    0.516
ADP19262.1
ABC transporter family protein 94.
  
   
 0.507
ADP15437.1
Hypothetical protein.
  
     0.495
ADP15901.1
Rossmann fold nucleotide-binding protein-like domain protein.
  
     0.460
ADP13657.1
2Fe-2S iron-sulfur cluster binding domain protein 1.
  
     0.433
ADP13656.1
TENA/THI-4/PQQC family protein 1.
  
   
 0.424
grpE
Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]
      
 0.407
Your Current Organism:
Achromobacter xylosoxidans
NCBI taxonomy Id: 762376
Other names: A. xylosoxidans A8, Achromobacter xylosoxidans A8, Achromobacter xylosoxidans str. A8, Achromobacter xylosoxidans strain A8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.