Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADP15931.1Aldehyde dehydrogenase family protein 1; Belongs to the aldehyde dehydrogenase family. (522 aa)    
Predicted Functional Partners:
gabT1
4-aminobutyrate transaminase 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.933
gabT2
4-aminobutyrate transaminase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.933
mmsA2
Methylmalonate-semialdehyde dehydrogenase (acylating) 2.
  
  
 
0.921
ADP16618.1
Zinc-binding dehydrogenase family protein 6.
  
 0.921
ADP16984.1
Zinc-binding dehydrogenase family protein 7.
  
 0.921
adh2
Alcohol dehydrogenase 2.
  
 0.921
adhC
S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 0.920
mmsA1
Methylmalonate-semialdehyde dehydrogenase (acylating) 1.
  
  
 
0.918
mmsA3
Methylmalonate-semialdehyde dehydrogenase (acylating) 3.
  
  
 
0.918
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.916
Your Current Organism:
Achromobacter xylosoxidans
NCBI taxonomy Id: 762376
Other names: A. xylosoxidans A8, Achromobacter xylosoxidans A8, Achromobacter xylosoxidans str. A8, Achromobacter xylosoxidans strain A8
Server load: medium (42%) [HD]